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Filtered Search Results
eMolecules 2-Phenyl-1,1,1-trifluoropropan-2-ol | 426-54-0 | MFCD07366525 | 1g
Combi-Blocks | 2-Phenyl-1,1,1-trifluoropropan-2-ol | 1g | 517028759 | QC-2650 | 95.000 | 426-54-0 | MFCD07366525 | 190.165 | C9H9F3O
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Medchemexpress LLC 5-O-Methylvisammioside | 84272-85-5 | 452.45 | 50 MG
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5-O-Methylvisammioside is a natural compound isolated from Saposhnikovia divaricata.
- Natural compound
- Isolated from Saposhnikovia divaricata
- Purity: 99.90%
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![eMolecules 3-methylsulfonylbicyclo[1.1.1]pentane-1-carboxylic acid | 1886967-73-2 | MFCD30803688 | 100mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502159073.JPG-250.jpg)
eMolecules 3-methylsulfonylbicyclo[1.1.1]pentane-1-carboxylic acid | 1886967-73-2 | MFCD30803688 | 100mg
Pharmablock | 3-methylsulfonylbicyclo[1.1.1]pentane-1-carboxylic acid | 100mg | 551308078 | PBZ2638 | | 1886967-73-2 | MFCD30803688 | 190.210 | C7H10O4S
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Medchemexpress LLC CSK-IN-1 | 2380027-49-4 | 98.6% | 50 MG
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CSK-IN-1 (compound 13) is a potent, orally active c-terminal Src kinase (CSK) inhibitor with IC50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. It increases T cell proliferation induced by T cell receptor signaling. This product is for research use only.
- Potent, orally active c-terminal Src kinase (CSK) inhibitor
- Achieves IC50 values below 3 nM in CSK HTRF assay
- Achieves IC50 values below 4 nM in Caliper assay
- Increases T cell proliferation induced by T cell receptor signaling
- Reduces inhibitory LCK phosphorylation in vivo upon oral dosing
- Enhances T cell activation in response to antigen stimulation
- Shows EC50 of 41 nM on ZAP70 phosphorylation in human Jurkat cells
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Medchemexpress LLC Tak1-in-2 | 2763213-98-3 | 98.8% | C26H26F2N6O5 | 10MG
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TAK1-IN-2 is a potent, selective small-molecule inhibitor of transforming growth factor-β-activated kinase 1 (TAK1) for laboratory research. It exhibits low-nanomolar potency (IC50 = 2 nM) and is supplied as a high-purity compound for in vitro and preclinical studies; not for human or clinical use.
- Potent TAK1 inhibition (IC50 = 2 nM).
- High selectivity reduces off-target kinase activity.
- High purity suitable for biochemical and cell-based assays.
- Available in multiple milligram pack sizes for dosing flexibility.
- Datasheet, certificate of analysis, and safety data sheet provided.
- Intended for research use only; not for human therapeutic use.
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Medchemexpress LLC Temanogrel | 887936-68-7 | 98.9% | 436.50 g·mol⁻¹ | C24H28N4O4 | 25 MG
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Temanogrel is a research-grade selective 5-HT2A receptor antagonist (reported Ki 4.9 nM) used to study serotonin receptor pharmacology and platelet function. Supplied as a solid for laboratory research use only, it is provided with stability information for short- and long-term storage.
- Selective 5-HT2A receptor antagonist (Ki 4.9 nM).
- High purity (98.9%).
- Solid form with white to light yellow appearance.
- Recommended storage conditions provided for solid and solution stability.
- Suitable for in vitro receptor binding and platelet function studies.
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Medchemexpress LLC GB-110 hydrochloride | 99.9% | 645.23 | 100 MG
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GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. It selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM.
- Potent and orally active
- Nonpeptidic compound
- Selective PAR2 agonist
- Induces Ca2+ release in HT29 cells
- Intended for research use only
- High purity
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Medchemexpress LLC HY-12023 5mg Medchemexpress, Andarine CAS:401900-40-1 Purity:>98%
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Medchemexpress, HY-12023 5mg Andarine CAS:401900-40-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Rg-12525 | 120128-20-3 | 98.3% | 423.47 g/mol | C25H21N5O2 | 25 MG
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RG-12525 is a small-molecule research compound reported as a potent antagonist of peptidoleukotrienes (LTC4, LTD4, LTE4); it also shows PPAR-gamma agonist activity and inhibits CYP3A4. Intended for in vitro and preclinical studies, the compound is supplied at high purity and is typically dissolved in DMSO for assays.
- Specific antagonist of peptidoleukotrienes with low-nanomolar activity
- Shows PPAR-gamma agonist activity (approx. IC50 60 nM)
- Inhibits CYP3A4 (Ki ≈ 0.5 μM)
- High purity suitable for preclinical research
- Soluble in DMSO for assay preparation
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![eMolecules Medchem Express / Rogaratinib / 1mg / 446254781 / HY-100019 / / 1443530-05-9 / [null] / 466.560 / C23H26N6O3S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502449217.PNG-250.jpg)
eMolecules Medchem Express / Rogaratinib / 1mg / 446254781 / HY-100019 / / 1443530-05-9 / [null] / 466.560 / C23H26N6O3S
Medchem Express / Rogaratinib / 1mg / 446254781 / HY-100019 / / 1443530-05-9 / [null] / 466.560 / C23H26N6O3S
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Biotium DIOC23 100MG
DIOC23 100MG
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Medchemexpress LLC TFMB-(R)-2-HG | 1445700-01-5 | 98.3% | 10 MG
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TFMB-(R)-2-HG is a cell membrane-permeable (R)-2-HG and an acute myeloid leukemia (AML) oncogenic factor. It functions by competitively inhibiting α-ketoglutarate-dependent dioxygenases, such as KDM2B and FTO. This compound impairs cell differentiation when there is estrogen withdrawal and is utilized in research concerning acute myeloid leukemia and glioma.
- Promotes growth factor-independent growth of TF-1 cells and inhibits their response to erythropoietin (EPO) in a dose- and passage-dependent manner.
- Significantly enhances anchorage-independent growth of N::TVA;Cdkn2alox/lox;Atrxlox/lox;Ptenlox/lox astrocytes.
- Significantly suppresses global 5hmC levels in TF-1 cells and transforms TF-1 cells.
- Inhibits the differentiation of SCF ER-Hoxb8 cells after estrogen withdrawal in mice.
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Medchemexpress LLC HY-W050000 100mg Medchemexpress, OR-1855 CAS:101328-85-2 Purity:>98%
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Medchemexpress, HY-W050000 100mg OR-1855 CAS:101328-85-2 OR-1855, an active metabolite of Levosimendan, has effect on human myometrial contractility. Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100183 50mg Medchemexpress, GSK2239633A CAS:1240516-71-5 Purity:>98%
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Medchemexpress, HY-100183 50mg GSK2239633A CAS:1240516-71-5 GSK2239633A is a CC-chemokine receptor 4 ( CCR4 ) antagonist, which inhibits the binding of [ 125 I]-TARC to human CCR4 with a pIC 50 of 7.96 ± 0.11. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / Cenerimod / 5mg / 446268733 / HY-17606 / / 1262414-04-9 / MFCD30530772 / 453.539 / C25H31N3O5
Medchem Express / Cenerimod / 5mg / 446268733 / HY-17606 / / 1262414-04-9 / MFCD30530772 / 453.539 / C25H31N3O5
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